How does this medication work? What will it do for me?🔎
Capecitabine belongs to the group of cancer-fighting medications known as antineoplastics, and specifically to the group of antineoplastics known as antimetabolites. Capecitabine fights cancer by killing cancer cells and preventing their growth. Capecitabine may be used alone or in combination with other medications to treat certain types of breast cancer and colorectal cancer.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
What form(s) does this medication come in?📌
150 mg
Each light-peach-coloured, biconvex, film-coated, oblong tablet with "XELODA" engraved on one side and "150" on the other contains 150 mg of capecitabine. Nonmedicinal ingredients: croscarmellose sodium, hydroxypropyl methylcellulose, lactose anhydrous, magnesium stearate, microcrystalline cellulose, synthetic red iron oxide, synthetic yellow iron oxide, talc, and titanium dioxide.
500 mg
Each peach-colored, biconvex, film-coated, oblong tablet with "XELODA" engraved on one side and "500" on the other contains 500 mg of capecitabine. Nonmedicinal ingredients: croscarmellose sodium, hydroxypropyl methylcellulose, lactose anhydrous, magnesium stearate, microcrystalline cellulose, synthetic red iron oxide, synthetic yellow iron oxide, talc, and titanium dioxide.
How should I use this medication?👓
The recommended dose of capecitabine varies according to body size. You may need to take a combination of 150 mg and 500 mg tablets. Capecitabine is normally given in 2 equal doses twice a day for 2 weeks followed by a rest period of one week. This cycle is repeated until treatment is complete, as assessed by your doctor.
Capecitabine tablets should be swallowed with water within 30 minutes after the end of a meal.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important that you take this medication exactly as prescribed by your doctor. If you vomit shortly after taking capecitabine, contact your doctor for instruction on whether to take more medication or not. If you miss a dose of this medication, skip the missed dose and go back to your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature in its original container, protect it from excessive heat and direct light, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Who should NOT take this medication?❌
Do not take capecitabine if you:
-are allergic to capecitabine, 5-fluorouracil, or to any of the ingredients of the medication
-are being treated or have been treated in the last 4 weeks with brivudine or sorivudine as part of herpes zoster (chickenpox or shingles) therapy
-have dihydropyrimidine dehydrogenase (DPD) deficiency
-have severely reduced kidney function
Capecitabine belongs to the group of cancer-fighting medications known as antineoplastics, and specifically to the group of antineoplastics known as antimetabolites. Capecitabine fights cancer by killing cancer cells and preventing their growth. Capecitabine may be used alone or in combination with other medications to treat certain types of breast cancer and colorectal cancer.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
What form(s) does this medication come in?📌
150 mg
Each light-peach-coloured, biconvex, film-coated, oblong tablet with "XELODA" engraved on one side and "150" on the other contains 150 mg of capecitabine. Nonmedicinal ingredients: croscarmellose sodium, hydroxypropyl methylcellulose, lactose anhydrous, magnesium stearate, microcrystalline cellulose, synthetic red iron oxide, synthetic yellow iron oxide, talc, and titanium dioxide.
500 mg
Each peach-colored, biconvex, film-coated, oblong tablet with "XELODA" engraved on one side and "500" on the other contains 500 mg of capecitabine. Nonmedicinal ingredients: croscarmellose sodium, hydroxypropyl methylcellulose, lactose anhydrous, magnesium stearate, microcrystalline cellulose, synthetic red iron oxide, synthetic yellow iron oxide, talc, and titanium dioxide.
How should I use this medication?👓
The recommended dose of capecitabine varies according to body size. You may need to take a combination of 150 mg and 500 mg tablets. Capecitabine is normally given in 2 equal doses twice a day for 2 weeks followed by a rest period of one week. This cycle is repeated until treatment is complete, as assessed by your doctor.
Capecitabine tablets should be swallowed with water within 30 minutes after the end of a meal.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important that you take this medication exactly as prescribed by your doctor. If you vomit shortly after taking capecitabine, contact your doctor for instruction on whether to take more medication or not. If you miss a dose of this medication, skip the missed dose and go back to your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature in its original container, protect it from excessive heat and direct light, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Who should NOT take this medication?❌
Do not take capecitabine if you:
-are allergic to capecitabine, 5-fluorouracil, or to any of the ingredients of the medication
-are being treated or have been treated in the last 4 weeks with brivudine or sorivudine as part of herpes zoster (chickenpox or shingles) therapy
-have dihydropyrimidine dehydrogenase (DPD) deficiency
-have severely reduced kidney function
💊Where can buy Xeloda (capecitabine).💊
For the Consumer
Applies to capecitabine: oral tablet
Along with its needed effects, capecitabine (the active ingredient contained in Xeloda) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Xeloda side effects>>>>>https://www.drugs.com/xeloda.html
ReplyDeleteGet emergency medical help if you have signs of an allergic reaction to Xeloda: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
What it Treats
ReplyDeleteXeloda is a prescription medicine used to treat people with:
cancer of the colon that has spread to lymph nodes in the area close to the colon (Dukes’ C stage), after they have surgery.
cancer of the colon or rectum (colorectal) that has spread to other parts of the body (metastatic).
breast cancer that has spread to other parts of the body (metastatic) together with another medicine called docetaxel after treatment with certain other anticancer medicines have not worked.
breast cancer that has spread to other parts of the body and has not improved after treatment with paclitaxel and certain other anti-cancer medicines, or who cannot receive any more treatment with certain anti-cancer medicines.
It is not known if Xeloda is safe and effective in children.
And...
Capcytobine A prodrug of the chemotherapeutic 5-fluorouracil (5-FU), which is used to treat metastatic breast and colorectal cancers. 5-FU inhibits DNA synthesis and slows tumour proliferation.
ReplyDeleteSelf-Care Tips:
ReplyDeleteDrink at least two to three quarts of fluid every 24 hours, unless you are instructed otherwise.
You may be at risk of infection so try to avoid crowds or people with colds, and report fever or any other signs of infection immediately to you health care provider.
Wash your hands often.
To help treat/prevent mouth sores, use a soft toothbrush, and rinse three times a day with 1/2 to 1 teaspoon of baking soda and/or 1/2 to 1 teaspoon of salt mixed with 8 ounces of water.
Use an electric razor and a soft toothbrush to minimize bleeding.
Avoid contact sports or activities that could cause injury.
To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals.
Prevention of hand-foot syndrome. Modification of normal activities of daily living to reduce friction and heat exposure to hands and feet, as much as possible during treatment with capecitabine. (for more information see - Managing side effects: hand foot syndrome).
Keeps palms of hands and soles of feet moist using emollients such as Aveeno®, Udder cream, Lubriderm® or Bag Balm®.
Follow regimen of anti-diarrhea medication as prescribed by your health care professional.
Eat foods that may help reduce diarrhea (see managing side effects - diarrhea).
Avoid sun exposure. Wear SPF 30 (or higher) sunblock and protective clothing.
You may experience drowsiness or dizziness; avoid driving or engaging in tasks that require alertness until your response to the drug is known.
In general, drinking alcoholic beverages should be kept to a minimum or avoided completely. You should discuss this with your doctor.
Get plenty of rest.
Maintain good nutrition.
If you experience symptoms or side effects, be sure to discuss them with your health care team. They can prescribe medications and/or offer other suggestions that are effective in managing such problems.
A 62-year-old Singapore man was temporarily denied entry into the U.S. because a cancer drug he was taking had made his fingerprints disappear, according to a letter published in the Annals of Oncology. :(
ReplyDeleteSpeaking a s someone who is probably going to be on xeloda soon, I would like to hear some xeloda success stories.
ReplyDeleteI may not want to know but i`m curious about side effects.
Of course, the doctors make it sound like its no big deal.
I`ve had the drip before and i hated it but the supposedly the pills are more potent with less side effects.
I dont see how there would be less side effects when i am taking the chemo daily.
When I was doing the drip I couldnt wait to get unhooked from that crap and get as far away from that stuff as possible.
Im on 3000 mg a day. Side effects not bad. I do have problems with dry/cracked/blisters on hands and feet. I can't hike anymore but otherwise doesn't interfere with function so far.
ReplyDeleteLeukeran is a cancer medication which is used to treat certain types of cancer (leukemia, lymphoma, Hodgkin's disease).
ReplyDeleteGeneral information
Leukeran belongs to the group of medications known as antineoplastics. It contains chlorambucil. This medication works by preventing the growth of cancer cells by interfering with the genetic material DNA, which is necessary for reproduction of cells. Leukeran is used to treat certain types of cancer (leukemia, lymphoma, Hodgkin's disease). This drug may also be used for certain blood diseases, certain types of kidney disease in children that have not responded to other treatment.
Directions
Take Leukeran exactly as prescribed by your doctor. Take this medication by mouth. Drink plenty of fluids while taking this medication to prevent side effects. For chronic lymphocytic leukemia, the usual adult starting dose is 0.15 mg per kilogram body weight per day until the total white blood cell count reaches the desired range. 4 weeks after the first course of treatment, the medication may be restarted at a dose of 0.1 mg per kilogram body weight per day. For Hodgkin's disease, the usual dose is 0.2 mg per kilogram body weight per day for 4 to 8 weeks. For non-Hodgkin's lymphoma, the usual dose is 0.1 mg to 0.2 mg per kilogram body weight per day for 4 to 8 weeks initially.
Precautions
Before taking Leukeran you should talk with your doctor if you have seizures, head injury, gout, kidney stones, blood disorders (anemia, neutropenia, thrombocytopenia). Avoid contact with people who have contagious infections. Do not have immunizations or vaccinations without the consent of your doctor.
Contraindications
Do not take Leukeran if you are allergic to chlorambucil or any ingredients of this medication, are pregnant or breastfeeding, or if you have had a full course of radiation or chemotherapy within the previous 4 weeks.
Possible side effect
Get emergency medical help if you have changes in menstrual period, diarrhea, nausea, vomiting, muscle twitching, seizures, skin rash, tremors, unexpected bleeding, difficult urination, unusual tiredness, yellow eyes or skin, black or bloody stools, hives, difficulty breathing, swelling of the throat, mouth, joint pain, pale skin, stomach pain, loss of appetite, dark urine, sore throat, weakness, severe dizziness. If you notice other effects not listed above, contact your doctor.
Drug interactions
Tell your doctor about all other medications you use, especially: live vaccines (mumps, measles, yellow fever), natalizumab, phenylbutazone, pimecrolimus, roflumilast. Interaction between two medications does not always mean that you must stop taking one of them. Tell your doctor or prescriber about all prescription, over-the-counter, and herbal medications you are taking.
Missed dose
Take the missed dose as soon as possible. Skip the missed dose if it is time for your next scheduled dose. Don't take extra medicine to make up the missed dose.
Overdose
If you think you have overdosed the medicine seek emergency medical help at once. The overdose symptoms are loss of balance, excitation, convulsions.
Storage
Store the medicine at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture. Keep all drugs away from reach of children and pets.
https://plus.google.com/u/0/collection/AnZHOE
Lee Hadwiger and Kiwamu Tanaka from the WSU Department of Plant Pathology used anticancer drugs that change the DNA of cancer cells to slow or stop their growth when used in high levels on humans. But when the drugs are used in low levels in plants, they affect a cell's DNA by activating genes used to defend against pathogens.
ReplyDeleteThe researchers applied a wide array of DNA-specific drugs, including actinomycin D, also known as dactinomycin, to pea tissue. There generally were two different results from those applications, with differing mechanisms of action.
First, the plants started producing higher levels of an antimicrobial substance called pisatin, a known marker that shows a plant's defense system is turning on.
Then, the scientists exposed the treated plants to fungal infections. The exposed plants stopped the infection within hours.
Hadwiger and Tanaka don't foresee using anticancer medications on crops, but this discovery helps build a deeper understanding of how the chemicals interact with plant DNA.
"We used these drugs as a tool to understand how plants defend themselves from pathogens," said Hadwiger. "We now understand how these defense genes can be activated and are using that knowledge to develop disease resistance against fungal infections and other pathogens."