* Generic Name: amiloride and hydrochlorothiazide
* Brand Name: Moduretic
* What is hydrochlorothiazide and amiloride (Moduretic 5-50)?
* What are the possible side effects of hydrochlorothiazide and
amiloride (Moduretic 5-50)?
* What is the most important information I should know about
hydrochlorothiazide and amiloride (Moduretic 5-50)?
* What should I discuss with my healthcare provider before taking
hydrochlorothiazide and amiloride (Moduretic 5-50)?
* How should I take hydrochlorothiazide and amiloride (Moduretic
5-50)?
* What happens if I miss a dose (Moduretic 5-50)?
* What happens if I overdose (Moduretic 5-50)?
* What should I avoid while taking hydrochlorothiazide and
amiloride (Moduretic 5-50)?
* What other drugs will affect hydrochlorothiazide and amiloride
(Moduretic 5-50)?
* Where can I get more information (Moduretic 5-50)?
What is hydrochlorothiazide and amiloride (Moduretic 5-50)?
Hydrochlorothiazide is a thiazide diuretic (water pill) that helps
prevent your body from absorbing too much salt, which can cause fluid
retention.
Amiloride is a potassium sparing-diuretic that also prevents your
body from absorbing too much salt and keeps your potassium levels from
getting too low.
The combination of hydrochlorothiazide and amiloride is used to treat
fluid retention (edema) and high blood pressure (hypertension).
Hydrochlorothiazide and amiloride may also be used for purposes not
listed in this medication guide.
What are the possible side effects of hydrochlorothiazide and amiloride
(Moduretic 5-50)?
Get emergency medical help if you have signs of an allergic reaction:
hives; difficulty breathing; swelling of your face, lips, tongue, or
throat.
Call your doctor at once if you have:
* a light-headed feeling, like you might pass out;
* high sodium--headache, confusion, slurred speech,
hallucinations, vomiting, severe weakness, muscle
cramps, loss of coordination, feeling unsteady, shallow breathing;
or
* high potassium--slow heart rate, weak pulse, muscle weakness,
tingly feeling.
Common side effects may include:
* diarrhea, constipation;
* mild stomach pain; or
* tired feeling.
This is not a complete list of side effects and others may occur. Call
your doctor for medical advice about side effects. You may report side
effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about
hydrochlorothiazide and amiloride (Moduretic 5-50)?
You should not use this medicine if you have kidney disease, urination
problems, diabetes, or high levels of potassium in your blood.
Some medicines can cause unwanted or dangerous effects when used with
hydrochlorothiazide and amiloride. Your doctor may need to change your
treatment plan if you use potassium supplements or certain
diuretics (spironolactone, triamterene).
If you have diabetes, do not use hydrochlorothiazide and amiloride
together with any medication that contains aliskiren (Amturnide,
Tekturna, Tekamlo, Valturna).
Moduretic Patient Information including How Should I Take
High Blood Pressure: Learn About Hypertension
High Blood Pressure Slideshow Pictures
RxList
Take the Salt Quiz!
Lowering Blood Pressure:Exercise Tips for Getting Started
Lowering Blood Pressure Exercise Tips Pictures
What should I discuss with my healthcare provider before taking
hydrochlorothiazide and amiloride (Moduretic 5-50)?
You should not use this medication if you are allergic to
hydrochlorothiazide or amiloride, or if you have:
* kidney disease or are unable to urinate;
* high potassium levels (hyperkalemia); or
* if you are taking potassium supplements.
Some medicines can cause unwanted or dangerous effects when used with
hydrochlorothiazide and amiloride. Your doctor may need to change your
treatment plan if you use potassium supplements or certain diuretics
(spironolactone, triamterene).
If you have diabetes, do not use hydrochlorothiazide and amiloride
together with any medication that contains aliskiren (Amturnide,
Tekturna, Tekamlo, Valturna).
To make sure hydrochlorothiazide and amiloride is safe for you, tell
your doctor if you have:
* high cholesterol, heart disease, coronary artery
disease;
* cirrhosis or other liver disease;
* glaucoma;
* a breathing disorder;
* gout; or
* an allergy to sulfa drugs or penicillin.
This medication is not expected to be harmful to an unborn baby. Tell
your doctor if you are pregnant or plan to become pregnant during
treatment.
Hydrochlorothiazide can pass into breast milk and may harm a nursing
baby. You should not breast-feed while you are using
hydrochlorothiazide and amiloride.
How should I take hydrochlorothiazide and amiloride (Moduretic 5-50)?
Follow all directions on your prescription label. Do not take this
medicine in larger or smaller amounts or for longer than recommended.
Take hydrochlorothiazide and amiloride with food.
Your blood pressure will need to be checked often. Your blood and urine
may also be tested if you have been vomiting or are dehydrated.
If you need surgery or medical tests, tell the doctor ahead of time
that you are taking medication that contains hydrochlorothiazide. You
may need to stop using the medicine for a short time.
If you are being treated for high blood pressure, keep using this
medication even if you feel well. High blood pressure often has no
symptoms. You may need to use blood pressure medication for the rest of
your life.
Store at room temperature away from moisture, heat, and light. Do not
freeze.
Moduretic Patient Information including If I Miss a Dose
High Blood Pressure: Learn About Hypertension
High Blood Pressure Slideshow Pictures
RxList
Take the Salt Quiz!
Lowering Blood Pressure:Exercise Tips for Getting Started
Lowering Blood Pressure Exercise Tips Pictures
What happens if I miss a dose (Moduretic 5-50)?
Take the missed dose as soon as you remember. Skip the missed dose if
it is almost time for your next scheduled dose. Do not take extra
medicine to make up the missed dose.
What happens if I overdose (Moduretic 5-50)?
Seek emergency medical attention or call the Poison Help line at
1-800-222-1222.
What should I avoid while taking hydrochlorothiazide and amiloride (Moduretic
5-50)?
Drinking alcohol can increase certain side effects of
hydrochlorothiazide and amiloride.
Do not use salt substitutes or low-sodium milk products that contain
potassium. These products could cause your potassium levels to get too
high while you are taking hydrochlorothiazide and amiloride.
Avoid a diet high in salt. Too much salt will cause your body to
retain water and can make this medication less effective.
This medication may impair your thinking or reactions. Be careful if
you drive or do anything that requires you to be alert.
Avoid becoming overheated or dehydrated during exercise and in hot
weather. Follow your doctor's instructions about the type and amount of
liquids you should drink. In some cases, drinking too much liquid can
be as unsafe as not drinking enough.
What other drugs will affect hydrochlorothiazide and amiloride (Moduretic
5-50)?
Tell your doctor if you regularly use other medicines that make you
light-headed (such as cold medicine, a sleeping pill, narcotic pain
medicine, muscle relaxer, or medicine for anxiety, depression, or
seizures). They can add to the side effects of hydrochlorothiazide and
amiloride.
Tell your doctor about all medicines you use, and those you start or
stop using during your treatment with hydrochlorothiazide and
amiloride, especially:
* lithium;
* tacrolimus; or
* other blood pressure medications.
This list is not complete. Other drugs may interact with
hydrochlorothiazide and amiloride, including prescription and
over-the-counter medicines, vitamins, and herbal products. Not all
possible interactions are listed in this medication guide.
Where can I get more information (Moduretic 5-50)?
Your pharmacist can provide more information about hydrochlorothiazide
and amiloride.
__________________________________________________________________
Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this
medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by
Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
but no guarantee is made to that effect. Drug information contained
herein may be time sensitive. Multum information has been compiled for
use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United
States are appropriate, unless specifically indicated otherwise.
Multum's drug information does not endorse drugs, diagnose patients or
recommend therapy. Multum's drug information is an informational
resource designed to assist licensed healthcare practitioners in caring
for their patients and/or to serve consumers viewing this service as a
supplement to, and not a substitute for, the expertise, skill,
knowledge and judgment of healthcare practitioners. The absence of a
warning for a given drug or drug combination in no way should be
construed to indicate that the drug or drug combination is safe,
effective or appropriate for any given patient. Multum does not assume
any responsibility for any aspect of healthcare administered with the
aid of information Multum provides. The information contained herein is
not intended to cover all possible uses, directions, precautions,
warnings, drug interactions, allergic reactions, or adverse effects. If
you have questions about the drugs you are taking, check with your
doctor, nurse or pharmacist.
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