* Generic Name: esomeprazole magnesium
* Brand Name: Nexium
* What is esomeprazole?
* What are the possible side effects of esomeprazole?
* What is the most important information I should know about
esomeprazole?
* What should I discuss with my healthcare provider before taking
esomeprazole?
* How should I take esomeprazole?
* What happens if I miss a dose?
* What happens if I overdose?
* What should I avoid while taking esomeprazole?
* What other drugs will affect esomeprazole?
* Where can I get more information?
What is esomeprazole?
Esomeprazole is a proton pump inhibitor that decreases the amount
of acid produced in the stomach.
Esomeprazole is used to treat symptoms of gastroesophageal reflux
disease (GERD) and other conditions involving excessive stomach
acid such as Zollinger-Ellison syndrome. Esomeprazole is also used
to promote healing of erosive esophagitis (damage to your
esophagus caused by stomach acid).
Esomeprazole may also be given to prevent gastric ulcer caused by
infection with helicobacter pylori (H. pylori), or by the use of
nonsteroidal anti-inflammatory drugs (NSAIDs).
Esomeprazole is not for immediate relief of heartburn symptoms.
Esomeprazole may also be used for purposes not listed in this
medication guide.
What are the possible side effects of esomeprazole?
Get emergency medical help if you have signs of an allergic reaction:
hives; difficulty breathing; swelling of your face, lips, tongue, or
throat.
Call your doctor at once if you have:
* severe stomach pain, diarrhea that is watery or bloody;
* seizure (convulsions);
* joint pain or swelling with fever, swollen glands, and skin
rash on your cheeks or arms (worsens in sunlight);
* kidney problems--urinating more or less than usual, blood in your
urine, swelling, rapid weight gain; or
* low magnesium--dizziness, irregular heartbeats, feeling jittery,
muscle cramps, muscle spasms, cough or choking feeling.
Taking esomeprazole long-term may cause you to develop stomach growths
called fundic gland polyps. Talk with your doctor about this risk.
Common side effects may include:
* headache, drowsiness;
* mild diarrhea;
* nausea, stomach pain, gas, constipation; or
* dry mouth.
This is not a complete list of side effects and others may occur. Call
your doctor for medical advice about side effects. You may report side
effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about esomeprazole?
Follow all directions on your medicine label and package. Tell each of
your healthcare providers about all your medical conditions, allergies,
and all medicines you use.
Nexium Patient Information including How Should I Take
Heartburn:Foods to Eat, Foods to Avoid
Heartburn? Foods to Eat, Foods to Avoid Slideshow
Digestive Disease Myths:Common Misconceptions
Digestive Disease Myths Slideshow Pictures
RxList
Take the GERD Quiz
What should I discuss with my healthcare provider before taking esomeprazole?
Heartburn can mimic early symptoms of a heart attack. Get
emergency medical help if you have chest pain that spreads to your jaw
or shoulder and you feel anxious or light-headed.
You should not use this medicine if you are allergic to esomeprazole or
to similar medicines such as lansoprazole (Prevacid),
omeprazole (Prilosec, Zegerid), pantoprazole
(Protonix), or rabeprazole (AcipHex).
Tell your doctor if you have ever had:
* severe liver disease;
* lupus;
* osteoporosis or low bone mineral density (osteopenia);
or
* low levels of magnesium in your blood.
You may be more likely to have a broken bone in your hip, wrist, or
spine while taking a proton pump inhibitor. Talk with your doctor about
ways to keep your bones healthy.
Ask a doctor before using this medicine if you are pregnant or
breast-feeding.
How should I take esomeprazole?
Use exactly as directed on the label, or as prescribed by your doctor.
This medicine is usually given for 4 to 8 weeks only. Your doctor may
recommend a second course of treatment if you need additional healing
time.
Take each dose with a full glass (8 ounces) of water.
Esomeprazole should be taken at least one hour before a meal.
Swallow the capsule whole and do not crush, chew, break, or open it.
If you cannot swallow a capsule whole, open it and sprinkle the
medicine into a spoonful of pudding or applesauce. Swallow the mixture
right away without chewing. Do not save it for later use.
The esomeprazole capsule can be given through a nasogastric
(NG) feeding tube. Read and carefully follow any Instructions
for Use provided with your medicine. Ask your doctor or pharmacist if
you do not understand these instructions.
Use this medicine for the full prescribed length of time, even if your
symptoms quickly improve.
Taking esomeprazole long-term could cause you to develop a vitamin B-12
deficiency. Talk to your doctor about how to manage this condition.
Call your doctor if your symptoms do not improve or if they get worse
while you are taking this medicine.
This medicine can affect the results of certain medical tests. Tell any
doctor who treats you that you are using esomeprazole.
Store at room temperature away from moisture and heat.
Nexium Patient Information including If I Miss a Dose
Heartburn:Foods to Eat, Foods to Avoid
Heartburn? Foods to Eat, Foods to Avoid Slideshow
Digestive Disease Myths:Common Misconceptions
Digestive Disease Myths Slideshow Pictures
RxList
Take the GERD Quiz
What happens if I miss a dose?
Use the medicine as soon as you can, but skip the missed dose if it is
almost time for your next dose. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at
1-800-222-1222.
What should I avoid while taking esomeprazole?
This medicine can cause diarrhea, which may be a sign of a new
infection. If you have diarrhea that is watery or bloody, call your
doctor before using anti-diarrhea medicine.
What other drugs will affect esomeprazole?
Tell your doctor about all your other medicines, especially:
* cilostazol;
* clopidogrel;
* diazepam;
* digoxin;
* erlotinib;
* iron-containing medicines (ferrous fumarate, ferrous gluconate,
ferrous sulfate, and others);
* methotrexate;
* mycophenolate mofetil;
* rifampin;
* St. John's wort;
* tacrolimus;
* warfarin (Coumadin, Jantoven);
* antifungal medication--ketoconazole, voriconazole; or
* HIV/AIDS medication--atazanavir, nelfinavir, saquinavir.
This list is not complete and many other drugs may affect esomeprazole.
This includes prescription and over-the-counter medicines, vitamins,
and herbal products. Not all possible drug interactions are listed
here.
Where can I get more information?
Your pharmacist can provide more information about esomeprazole.
__________________________________________________________________
Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this
medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by
Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
but no guarantee is made to that effect. Drug information contained
herein may be time sensitive. Multum information has been compiled for
use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United
States are appropriate, unless specifically indicated otherwise.
Multum's drug information does not endorse drugs, diagnose patients or
recommend therapy. Multum's drug information is an informational
resource designed to assist licensed healthcare practitioners in caring
for their patients and/or to serve consumers viewing this service as a
supplement to, and not a substitute for, the expertise, skill,
knowledge and judgment of healthcare practitioners. The absence of a
warning for a given drug or drug combination in no way should be
construed to indicate that the drug or drug combination is safe,
effective or appropriate for any given patient. Multum does not assume
any responsibility for any aspect of healthcare administered with the
aid of information Multum provides. The information contained herein is
not intended to cover all possible uses, directions, precautions,
warnings, drug interactions, allergic reactions, or adverse effects. If
you have questions about the drugs you are taking, check with your
doctor, nurse or pharmacist.
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