* Generic Name: quetiapine fumarate
* Brand Name: Seroquel
* What is quetiapine (SEROquel, SEROquel XR)?
* What are the possible side effects of quetiapine (SEROquel,
SEROquel XR)?
* What is the most important information I should know about
quetiapine (SEROquel, SEROquel XR)?
* What should I discuss with my healthcare provider before taking
quetiapine (SEROquel, SEROquel XR)?
* How should I take quetiapine (SEROquel, SEROquel XR)?
* What happens if I miss a dose (SEROquel, SEROquel XR)?
* What happens if I overdose (SEROquel, SEROquel XR)?
* What should I avoid while taking quetiapine (SEROquel, SEROquel
XR)?
* What other drugs will affect quetiapine (SEROquel, SEROquel
XR)?
* Where can I get more information (SEROquel, SEROquel XR)?
What is quetiapine (SEROquel, SEROquel XR)?
Quetiapine is an antipsychotic medicine. It works by changing
the actions of chemicals in the brain.
Quetiapine is used to treat schizophrenia in adults and children
who are at least 13 years old.
Quetiapine is used to treat bipolar disorder (manic depression)
in adults and children who are at least 10 years old.
Quetiapine is also used together with antidepressant medications to
treat major depressive disorder in adults.
Extended-release quetiapine (Seroquel XR) is for use only in adults and
should not be given to anyone younger than 18 years old.
Quetiapine may also be used for purposes not listed in this medication
guide.
What are the possible side effects of quetiapine (SEROquel, SEROquel XR)?
Get emergency medical help if you have signs of an allergic reaction:
hives; difficulty breathing; swelling of your face, lips, tongue, or
throat.
Report any new or worsening symptoms to your doctor, such as: mood or
behavior changes, anxiety, panic attacks, trouble sleeping, or if
you feel impulsive, irritable, agitated, hostile, aggressive, restless,
hyperactive (mentally or physically), more depressed, or have thoughts
about suicide or hurting yourself.
Call your doctor at once if you have:
* twitching or uncontrollable movements of your eyes, lips,
tongue, face, arms, or legs;
* mask-like appearance of the face, trouble swallowing, problems with
speech;
* a light-headed feeling, like you might pass out;
* blurred vision, tunnel vision, eye pain, or seeing halos
around lights;
* severe nervous system reaction--very stiff (rigid) muscles, high
fever, sweating, confusion, fast or uneven heartbeats,
tremors, fainting;
* high blood sugar--increased thirst, increased urination,
hunger, dry mouth, fruity breath odor, drowsiness, dry skin,
blurred vision, weight loss; or
* low blood cell counts--sudden weakness or ill feeling, fever,
chills, cold or flu symptoms, cough, sore throat, red or
swollen gums, painful mouth sores, skin sores, trouble
breathing.
Common side effects may include:
* trouble with movement;
* dizziness, weakness;
* increased appetite, weight gain;
* sore throat;
* dry mouth; or
* nausea, vomiting, stomach pain, constipation.
This is not a complete list of side effects and others may occur. Call
your doctor for medical advice about side effects. You may report side
effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about quetiapine
(SEROquel, SEROquel XR)?
Some young people have thoughts about suicide when first taking
quetiapine. Stay alert to changes in your mood or symptoms. Report any
new or worsening symptoms to your doctor.
Quetiapine is not approved for use in psychotic conditions related to
dementia. Quetiapine may increase the risk of death in older adults
with dementia-related conditions.
Seroquel Patient Information including How Should I Take
Schizophrenia: Types, Causes, Symptoms, and Treatment
Schizophrenia Slideshow Pictures
RxList
Take the Schizophrenia Quiz
What should I discuss with my healthcare provider before taking quetiapine
(SEROquel, SEROquel XR)?
You should not use quetiapine if you are allergic to it.
Quetiapine is not approved for use in psychotic conditions related to
dementia. Quetiapine may increase the risk of death in older adults
with dementia-related conditions.
To make sure quetiapine is safe for you, tell your doctor if you have:
* liver or kidney disease;
* heart disease, heart rhythm problems, a history of heart
attack or stroke;
* high or low blood pressure;
* a history of low white blood cell (WBC) counts;
* abnormal thyroid tests or prolactin levels;
* seizures or epilepsy;
* cataracts;
* high cholesterol or triglycerides;
* a personal or family history of diabetes; or
* trouble swallowing.
Some young people have thoughts about suicide when first taking
quetiapine. Your doctor will need to check your progress at regular
visits. Your family or other caregivers should also be alert to changes
in your mood or symptoms.
Taking antipsychotic medication during the last 3 months of pregnancy
may cause problems in the newborn, such as withdrawal symptoms,
breathing problems, feeding problems, fussiness, tremors, and limp or
stiff muscles. However, you may have withdrawal symptoms or other
problems if you stop taking your medicine during pregnancy. If you
become pregnant while taking quetiapine, do not stop taking it without
your doctor's advice.
Quetiapine can pass into breast milk and may harm a nursing baby. You
should not breast-feed while you are using quetiapine.
Do not give quetiapine to a child without a doctor's advice.
Extended-release quetiapine (Seroquel XR) is for use only in adults and
should not be given to anyone younger than 18 years old.
How should I take quetiapine (SEROquel, SEROquel XR)?
Follow all directions on your prescription label. Never take quetiapine
in larger amounts, or for longer than recommended by your doctor. High
doses or long-term use of quetiapine can cause a serious movement
disorder that may not be reversible. Symptoms of this disorder include
tremors or other uncontrollable muscle movements.
Take this medicine with a full glass of water. You may take quetiapine
with or without food.
Do not crush, chew, or break an extended-release tablet. Swallow it
whole.
Quetiapine may cause you to have high blood sugar
(hyperglycemia). If you are diabetic, check your blood sugar levels
on a regular basis while you are taking quetiapine.
You should not stop using quetiapine suddenly. Stopping suddenly may
make your condition worse.
Blood pressure may need to be checked often in a child or teenager
taking quetiapine.
Quetiapine can cause you to have a false positive drug screening
test. If you provide a urine sample for drug screening, tell the
laboratory staff that you are taking quetiapine.
Store at room temperature away from moisture and heat.
Seroquel Patient Information including If I Miss a Dose
Schizophrenia: Types, Causes, Symptoms, and Treatment
Schizophrenia Slideshow Pictures
RxList
Take the Schizophrenia Quiz
What happens if I miss a dose (SEROquel, SEROquel XR)?
Take the missed dose as soon as you remember. Skip the missed dose if
it is almost time for your next scheduled dose. Do not take extra
medicine to make up the missed dose.
What happens if I overdose (SEROquel, SEROquel XR)?
Seek emergency medical attention or call the Poison Help line at
1-800-222-1222. An overdose of quetiapine can be fatal.
What should I avoid while taking quetiapine (SEROquel, SEROquel XR)?
Avoid drinking alcohol. Dangerous side effects could occur.
Quetiapine may impair your thinking or reactions. Avoid driving or
operating machinery until you know how this medicine will affect you.
Avoid getting up too fast from a sitting or lying position, or you may
feel dizzy. Dizziness or severe drowsiness can cause falls, fractures,
or other injuries.
Avoid becoming overheated or dehydrated during exercise and in hot
weather. You may be more prone to heat stroke.
What other drugs will affect quetiapine (SEROquel, SEROquel XR)?
Quetiapine can cause a serious heart problem if you use certain
medicines at the same time, including antibiotics, antidepressants,
heart rhythm medicine, antipsychotic medicines, and medicines to treat
cancer, malaria, HIV or AIDS. Tell your doctor about all
medicines you use, and those you start or stop using during your
treatment with quetiapine.
Taking quetiapine with other drugs that make you sleepy or slow your
breathing can cause dangerous or life-threatening side effects. Ask
your doctor before taking a sleeping pill, narcotic pain medicine,
prescription cough medicine, a muscle relaxer, or medicine for anxiety,
depression, or seizures.
Many drugs can interact with quetiapine. Not all possible interactions
are listed here. Tell your doctor about all your current medicines and
any you start or stop using, especially:
* antibiotic or antifungal medicine;
* antiviral medicine to treat hepatitis or HIV/AIDS;
* heart or blood pressure medicine;
* medicine to treat mental illness;
* St. John's wort;
* seizure medicine; or
* tuberculosis medicine.
This list is not complete and many other drugs can interact with
quetiapine. This includes prescription and over-the-counter medicines,
vitamins, and herbal products. Give a list of all your medicines to any
healthcare provider who treats you.
Where can I get more information (SEROquel, SEROquel XR)?
Your pharmacist can provide more information about quetiapine.
__________________________________________________________________
Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this
medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by
Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
but no guarantee is made to that effect. Drug information contained
herein may be time sensitive. Multum information has been compiled for
use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United
States are appropriate, unless specifically indicated otherwise.
Multum's drug information does not endorse drugs, diagnose patients or
recommend therapy. Multum's drug information is an informational
resource designed to assist licensed healthcare practitioners in caring
for their patients and/or to serve consumers viewing this service as a
supplement to, and not a substitute for, the expertise, skill,
knowledge and judgment of healthcare practitioners. The absence of a
warning for a given drug or drug combination in no way should be
construed to indicate that the drug or drug combination is safe,
effective or appropriate for any given patient. Multum does not assume
any responsibility for any aspect of healthcare administered with the
aid of information Multum provides. The information contained herein is
not intended to cover all possible uses, directions, precautions,
warnings, drug interactions, allergic reactions, or adverse effects. If
you have questions about the drugs you are taking, check with your
doctor, nurse or pharmacist.
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