* Generic Name: lisinopril and hydrochlorothiazide
* Brand Name: Zestoretic
* What is hydrochlorothiazide and lisinopril (Prinzide,
Zestoretic)?
* What are the possible side effects of hydrochlorothiazide and
lisinopril (Prinzide, Zestoretic)?
* What is the most important information I should know about
hydrochlorothiazide and lisinopril (Prinzide, Zestoretic)?
* What should I discuss with my healthcare provider before taking
hydrochlorothiazide and lisinopril (Prinzide, Zestoretic)?
* How should I take hydrochlorothiazide and lisinopril (Prinzide,
Zestoretic)?
* What happens if I miss a dose (Prinzide, Zestoretic)?
* What happens if I overdose (Prinzide, Zestoretic)?
* What should I avoid while taking hydrochlorothiazide and
lisinopril (Prinzide, Zestoretic)?
* What other drugs will affect hydrochlorothiazide and lisinopril
(Prinzide, Zestoretic)?
* Where can I get more information (Prinzide, Zestoretic)?
What is hydrochlorothiazide and lisinopril (Prinzide, Zestoretic)?
Hydrochlorothiazide is a thiazide diuretic (water pill) that helps
prevent your body from absorbing too much salt, which can cause fluid
retention.
Lisinopril is in an ACE inhibitor. ACE stands for angiotensin
converting enzyme. Lisinopril lowers blood pressure and also relieves
symptoms of fluid retention.
Hydrochlorothiazide and lisinopril is a combination medicine used to
treat hypertension (high blood pressure).
Hydrochlorothiazide and lisinopril may also be used for purposes not
listed in this medication guide.
What are the possible side effects of hydrochlorothiazide and lisinopril
(Prinzide, Zestoretic)?
Get emergency medical help if you have signs of an allergic reaction:
hives; severe stomach pain; difficulty breathing; swelling of your
face, lips, tongue, or throat.
Call your doctor at once if you have:
* a light-headed feeling, like you might pass out;
* eye pain, vision problems;
* little or no urination;
* weakness, drowsiness, or feeling restless;
* fever, chills, sore throat, mouth sores, trouble
swallowing;
* jaundice (yellowing of the skin or eyes);
* high potassium--nausea, tingly feeling, chest pain, irregular
heartbeats, loss of movement;
* low potassium--leg cramps, constipation, irregular heartbeats,
fluttering in your chest, extreme thirst, increased urination,
numbness or tingling, muscle weakness or limp feeling; or
* low levels of sodium in the body--headache, confusion, slurred
speech, severe weakness, vomiting, loss of coordination,
feeling unsteady.
Common side effects may include:
* cough;
* headache;
* dizziness; or
* tired feeling.
This is not a complete list of side effects and others may occur. Call
your doctor for medical advice about side effects. You may report side
effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about
hydrochlorothiazide and lisinopril (Prinzide, Zestoretic)?
Do not use if you are pregnant. If you become pregnant, stop taking
this medicine and tell your doctor right away.
You should not use this medicine if you have ever had angioedema,
if you are unable to urinate, or if you are allergic to sulfa drugs or
to any ACE inhibitor. Do not take hydrochlorothiazide and lisinopril
within 36 hours before or after taking medicine that contains
sacubatril (such as Entresto).
If you have diabetes, do not use hydrochlorothiazide and lisinopril
together with any medication that contains aliskiren (such as
Tekturna or Tekamlo).
Zestoretic Patient Information including How Should I Take
High Blood Pressure: Learn About Hypertension
High Blood Pressure Slideshow Pictures
RxList
Take the Salt Quiz!
Lowering Blood Pressure:Exercise Tips for Getting Started
Lowering Blood Pressure Exercise Tips Pictures
What should I discuss with my healthcare provider before taking
hydrochlorothiazide and lisinopril (Prinzide, Zestoretic)?
You should not use this medicine if you are allergic to
hydrochlorothiazide or lisinopril, or if:
* you have hereditary angioedema;
* you are unable to urinate;
* you recently took a heart medicine called sacubatril;
* you have an allergy to sulfa drugs; or
* you have ever had a severe allergic reaction to any ACE inhibitor
(benazepril, captopril, enalapril, fosinopril,
moexipril, perindopril, quinapril, ramipril, trandolapril).
Do not take hydrochlorothiazide and lisinopril within 36 hours before
or after taking medicine that contains sacubatril (such as Entresto).
If you have diabetes, do not use hydrochlorothiazide and lisinopril
together with any medication that contains aliskiren (such as Tekturna
or Tekamlo).
You may also need to avoid taking hydrochlorothiazide and lisinopril
with aliskiren if you have kidney disease.
To make sure hydrochlorothiazide and lisinopril is safe for you, tell
your doctor if you have:
* kidney disease (or if you are on dialysis);
* cirrhosis or other liver disease;
* glaucoma;
* heart disease or congestive heart failure;
* asthma or allergies;
* gout;
* lupus; or
* an allergy to sulfa drugs or penicillin.
Do not use if you are pregnant. If you become pregnant, stop taking
this medicine and tell your doctor right away. Lisinopril can cause
injury or death to the unborn baby if you take the medicine during your
second or third trimester.
This medicine can pass into breast milk and may harm a nursing baby.
Tell your doctor if you are breast-feeding a baby.
How should I take hydrochlorothiazide and lisinopril (Prinzide, Zestoretic)?
Follow all directions on your prescription label. Your doctor may
occasionally change your dose. Do not take this medicine in larger or
smaller amounts or for longer than recommended.
Take each dose with a full glass of water.
Call your doctor if you have ongoing vomiting or diarrhea, or if you
are sweating more than usual. You can easily become dehydrated while
taking this medicine. This can lead to very low blood pressure,
electrolyte disorders, or kidney failure.
While using hydrochlorothiazide and lisinopril, you may need frequent
blood tests at your doctor's office. Your blood pressure will need to
be checked often.
Keep using this medicine as directed, even if you feel well. High blood
pressure often has no symptoms. You may need to use blood pressure
medication for the rest of your life.
If you need surgery or medical tests, tell the doctor ahead of time
that you are taking medicine that contains hydrochlorothiazide.
Store at room temperature away from moisture, heat, and light.
Zestoretic Patient Information including If I Miss a Dose
High Blood Pressure: Learn About Hypertension
High Blood Pressure Slideshow Pictures
RxList
Take the Salt Quiz!
Lowering Blood Pressure:Exercise Tips for Getting Started
Lowering Blood Pressure Exercise Tips Pictures
What happens if I miss a dose (Prinzide, Zestoretic)?
Take the missed dose as soon as you remember. Skip the missed dose if
it is almost time for your next scheduled dose. Do not take extra
medicine to make up the missed dose.
What happens if I overdose (Prinzide, Zestoretic)?
Seek emergency medical attention or call the Poison Help line at
1-800-222-1222.
What should I avoid while taking hydrochlorothiazide and lisinopril
(Prinzide, Zestoretic)?
Drinking alcohol can further lower your blood pressure and may increase
certain side effects of this medicine.
Do not use potassium supplements or salt substitutes while you are
taking this medicine, unless your doctor has told you to.
Avoid getting up too fast from a sitting or lying position, or you may
feel dizzy. Get up slowly and steady yourself to prevent a fall.
Avoid becoming overheated or dehydrated during exercise, in hot
weather, or by not drinking enough fluids. Follow your doctor's
instructions about the type and amount of liquids you should drink. In
some cases, drinking too much liquid can be as unsafe as not drinking
enough.
What other drugs will affect hydrochlorothiazide and lisinopril (Prinzide,
Zestoretic)?
Other drugs may interact with hydrochlorothiazide and lisinopril,
including prescription and over-the-counter medicines, vitamins, and
herbal products. Tell each of your health care providers about all
medicines you use now and any medicine you start or stop using.
Where can I get more information (Prinzide, Zestoretic)?
Your pharmacist can provide more information about hydrochlorothiazide
and lisinopril.
__________________________________________________________________
Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this
medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by
Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
but no guarantee is made to that effect. Drug information contained
herein may be time sensitive. Multum information has been compiled for
use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United
States are appropriate, unless specifically indicated otherwise.
Multum's drug information does not endorse drugs, diagnose patients or
recommend therapy. Multum's drug information is an informational
resource designed to assist licensed healthcare practitioners in caring
for their patients and/or to serve consumers viewing this service as a
supplement to, and not a substitute for, the expertise, skill,
knowledge and judgment of healthcare practitioners. The absence of a
warning for a given drug or drug combination in no way should be
construed to indicate that the drug or drug combination is safe,
effective or appropriate for any given patient. Multum does not assume
any responsibility for any aspect of healthcare administered with the
aid of information Multum provides. The information contained herein is
not intended to cover all possible uses, directions, precautions,
warnings, drug interactions, allergic reactions, or adverse effects. If
you have questions about the drugs you are taking, check with your
doctor, nurse or pharmacist.
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