Celebrex

Celebrex

     * Generic Name: celecoxib
     * Brand Name: Celebrex


     * What is celecoxib (CeleBREX)?
     * What are the possible side effects of celecoxib (CeleBREX)?
     * What is the most important information I should know about
       celecoxib (CeleBREX)?
     * What should I discuss with my healthcare provider before taking
       celecoxib (CeleBREX)?
     * How should I take celecoxib (CeleBREX)?
     * What happens if I miss a dose (CeleBREX)?
     * What happens if I overdose (CeleBREX)?
     * What should I avoid while taking celecoxib (CeleBREX)?
     * What other drugs will affect celecoxib (CeleBREX)?
     * Where can I get more information (CeleBREX)?

What is celecoxib (CeleBREX)?

   Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID).
   Celecoxib works by reducing hormones that cause inflammation and pain
   in the body.

   Celecoxib is used to treat pain or inflammation caused by many
   conditions such as arthritis, ankylosing spondylitis, and
   menstrual pain. Celecoxib is used to treat juvenile rheumatoid
   arthritis in children who are at least 2 years old. Celecoxib is also
   used in the treatment of hereditary polyps in the colon.

   Celecoxib may also be used for purposes not listed in this medication
   guide.

What are the possible side effects of celecoxib (CeleBREX)?

   Get emergency medical help if you have signs of an allergic reaction:
   sneezing, runny or stuffy nose; wheezing or trouble
   breathing; hives; swelling of your face, lips, tongue, or throat.

   Get emergency medical help if you have signs of a heart attack or
   stroke: chest pain spreading to your jaw or shoulder, sudden
   numbness or weakness on one side of the body, slurred speech,
   feeling short of breath.

   Stop using celecoxib and call your doctor at once if you have:
     * the first sign of any skin rash, no matter how mild;
     * shortness of breath (even with mild exertion);
     * swelling or rapid weight gain;
     * signs of stomach bleeding--bloody or tarry stools, coughing up
       blood or vomit that looks like coffee grounds;
     * liver problems--nausea, upper stomach pain, itching, tired feeling,
       flu-like symptoms, loss of appetite, dark urine,
       clay-colored stools, jaundice (yellowing of the skin or eyes);
     * kidney problems--little or no urinating, painful or difficult
       urination, swelling in your feet or ankles, feeling tired or short
       of breath;
     * low red blood cells (anemia)--pale skin, feeling light-headed
       or short of breath, rapid heart rate, trouble concentrating; or
     * severe skin reaction--fever, sore throat, swelling in your face
       or tongue, burning in your eyes, skin pain followed by a red or
       purple skin rash that spreads (especially in the face or upper
       body) and causes blistering and peeling.

   Common side effects may include:
     * stomach pain, indigestion, gas, diarrhea;
     * swelling in your hands or feet;
     * dizziness;
     * rash; or
     * cold symptoms such as stuffy nose, sneezing, sore throat.

   This is not a complete list of side effects and others may occur. Call
   your doctor for medical advice about side effects. You may report side
   effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about celecoxib
(CeleBREX)?

   Celecoxib can increase your risk of fatal heart attack or stroke,
   especially if you use it long term or take high doses, or if you have
   heart disease. Do not use this medicine just before or after heart
   bypass surgery (coronary artery bypass graft, or CABG).

   Celecoxib may also cause stomach or intestinal bleeding, which can be
   fatal. These conditions can occur without warning while you are using
   celecoxib, especially in older adults. You should not take this
   medicine if you already have bleeding in your stomach or intestines.

   Celebrex Patient Information including How Should I Take
   Rheumatoid Arthritis Symptoms and Treatment

   Rheumatoid Arthritis Slideshow
   RxList

   Take the RA Quiz
   Rheumatoid Arthritis Exercises:Joint-Friendly Fitness Routines

   Joint-Friendly Exercises Slideshow

What should I discuss with my healthcare provider before taking celecoxib
(CeleBREX)?

   Celecoxib can increase your risk of fatal heart attack or stroke,
   especially if you use it long term or take high doses, or if you have
   heart disease. Even people without heart disease or risk factors could
   have a stroke or heart attack while taking this medicine.

   Do not use this medicine just before or after heart bypass surgery
   (coronary artery bypass graft, or CABG).

   Celecoxib may also cause stomach or intestinal bleeding, which can be
   fatal. These conditions can occur without warning while you are using
   celecoxib, especially in older adults.

   You should not use celecoxib if you are allergic to it, or if you have:
     * bleeding in your stomach or intestines;
     * an allergy to sulfa drugs; or
     * a history of asthma attack or severe allergic reaction after
       taking aspirin or an NSAID.

   To make sure celecoxib is safe for you, tell your doctor if you have:
     * heart disease, high blood pressure, high cholesterol,
       diabetes, or if you smoke;
     * a history of heart attack, stroke, or blood clot;
     * a history of stomach ulcers or bleeding;
     * asthma;
     * liver or kidney disease; or
     * fluid retention.

   Taking celecoxib during the last 3 months of pregnancy may harm the
   unborn baby. Tell your doctor if you are pregnant or plan to become
   pregnant while using celecoxib.

   Celecoxib can pass into breast milk and may harm a nursing baby. Tell
   your doctor if you are breast-feeding a baby.

   Celecoxib is not approved for use by anyone younger than 2 years old.

How should I take celecoxib (CeleBREX)?

   Follow all directions on your prescription label. Do not take this
   medicine in larger amounts or for longer than recommended. Use the
   lowest dose that is effective in treating your condition.

   You may take celecoxib with or without food.

   Take with food if celecoxib upsets your stomach.

   To make swallowing easier, you may open the celecoxib capsule and
   sprinkle the medicine into a spoonful of applesauce. Swallow right away
   without chewing. Discard the empty capsule. If you do not take the
   mixture right away, keep it in the refrigerator and take it within 6
   hours.

   If you use this medicine long-term, you may need frequent medical
   tests.

   Store at room temperature away from moisture and heat.

   Read all patient information, medication guides, and instruction sheets
   provided to you. Ask your doctor or pharmacist if you have any
   questions.

   Celebrex Patient Information including If I Miss a Dose
   Rheumatoid Arthritis Symptoms and Treatment

   Rheumatoid Arthritis Slideshow
   RxList

   Take the RA Quiz
   Rheumatoid Arthritis Exercises:Joint-Friendly Fitness Routines

   Joint-Friendly Exercises Slideshow

What happens if I miss a dose (CeleBREX)?

   Since celecoxib is sometimes used when needed, you may not be on a
   dosing schedule. If you are on a schedule, use the missed dose as soon
   as you remember. Skip the missed dose if it is almost time for your
   next scheduled dose. Do not use extra medicine to make up the missed
   dose.

What happens if I overdose (CeleBREX)?

   Seek emergency medical attention or call the Poison Help line at
   1-800-222-1222.

What should I avoid while taking celecoxib (CeleBREX)?

   Avoid drinking alcohol. It may increase your risk of stomach bleeding.

   Avoid taking aspirin or other NSAIDs while you are taking
   celecoxib.

   Ask a doctor or pharmacist before using any cold, allergy, or pain
   medication. Many medicines available over the counter contain aspirin
   or other medicines similar to celecoxib. Taking certain products
   together can cause you to get too much of this type of medication.
   Check the label to see if a medicine contains aspirin, ibuprofen,
   ketoprofen, or naproxen.

What other drugs will affect celecoxib (CeleBREX)?

   Ask your doctor before using celecoxib if you take an antidepressant
   such as citalopram, escitalopram, fluoxetine (Prozac),
   fluvoxamine, paroxetine, sertraline (Zoloft),
   trazodone, or vilazodone. Taking any of these medicines with an
   NSAID may cause you to bruise or bleed easily.

   Tell your doctor about all your current medicines and any you start or
   stop using, especially:
     * fluconazole;
     * lithium;
     * a blood thinner (warfarin, Coumadin, Jantoven);
     * heart or blood pressure medication, including a diuretic or
       "water pill"; or
     * steroid medicine (such as prednisone).

   This list is not complete. Other drugs may interact with celecoxib,
   including prescription and over-the-counter medicines, vitamins, and
   herbal products. Not all possible interactions are listed in this
   medication guide.

Where can I get more information (CeleBREX)?

   Your pharmacist can provide more information about celecoxib.
     __________________________________________________________________

   Remember, keep this and all other medicines out of the reach of
   children, never share your medicines with others, and use this
   medication only for the indication prescribed.
   Every effort has been made to ensure that the information provided by
   Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
   but no guarantee is made to that effect. Drug information contained
   herein may be time sensitive. Multum information has been compiled for
   use by healthcare practitioners and consumers in the United States and
   therefore Multum does not warrant that uses outside of the United
   States are appropriate, unless specifically indicated otherwise.
   Multum's drug information does not endorse drugs, diagnose patients or
   recommend therapy. Multum's drug information is an informational
   resource designed to assist licensed healthcare practitioners in caring
   for their patients and/or to serve consumers viewing this service as a
   supplement to, and not a substitute for, the expertise, skill,
   knowledge and judgment of healthcare practitioners. The absence of a
   warning for a given drug or drug combination in no way should be
   construed to indicate that the drug or drug combination is safe,
   effective or appropriate for any given patient. Multum does not assume
   any responsibility for any aspect of healthcare administered with the
   aid of information Multum provides. The information contained herein is
   not intended to cover all possible uses, directions, precautions,
   warnings, drug interactions, allergic reactions, or adverse effects. If
   you have questions about the drugs you are taking, check with your
   doctor, nurse or pharmacist.

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