* Generic Name: cabergoline
* Brand Name: Dostinex
* What is cabergoline (Dostinex)?
* What are the possible side effects of cabergoline (Dostinex)?
* What is the most important information I should know about
cabergoline (Dostinex)?
* What should I discuss with my health care provider before
taking cabergoline (Dostinex)?
* How should I take cabergoline (Dostinex)?
* What happens if I miss a dose (Dostinex)?
* What happens if I overdose (Dostinex)?
* What should I avoid while taking cabergoline (Dostinex)?
* What other drugs will affect cabergoline (Dostinex)?
* Where can I get more information (Dostinex)?
What is cabergoline (Dostinex)?
Cabergoline is a dopamine receptor agonist. It works by
reducing the amount of prolactin (a hormone) that is released from
the pituitary gland.
Cabergoline is used to treat a hormone imbalance in which there is too
much prolactin in the blood (also called hyperprolactinemia).
Cabergoline may also be used for purposes not listed in this medication
guide.
What are the possible side effects of cabergoline (Dostinex)?
Get emergency medical help if you have any of these signs of an
allergic reaction: hives; difficult breathing; swelling of your face,
lips, tongue, or throat.
Stop using cabergoline and call your doctor at once if you have a
serious side effect such as:
* feeling short of breath on exertion;
* chest discomfort, dry cough or hack;
* feeling weak or tired, loss of appetite, rapid weight loss;
* feeling like you might pass out;
* lower back pain;
* urinating less than usual or not at all; or
* swelling in your ankles or feet.
You may have increased sexual urges, unusual urges to gamble, or other
intense urges while taking this medication. Talk with your doctor if
you believe you have any intense or unusual urges while taking
cabergoline.
Less serious side effects may include:
* nausea, vomiting, stomach pain, gas, indigestion,
constipation;
* headache, depressed mood;
* dizziness, spinning sensation;
* drowsiness, nervousness;
* hot flashes;
* numbness or tingly feeling; or
* dry mouth.
This is not a complete list of side effects and others may occur. Call
your doctor for medical advice about side effects. You may report side
effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about cabergoline
(Dostinex)?
You should not use this medication if you are allergic to cabergoline,
or if you have uncontrolled high blood pressure, pregnancy-related
high blood pressure, a history of heart or breathing problems or heart
valve disorder, or if you are allergic to any type of ergot
medicine such as ergotamine (Ergomar, Cafergot, Migergot),
dihydroergotamine (D.H.E. 45, Migranal), ergonovine (Ergotrate), or
methylergonovine (Methergine).
Before taking cabergoline, tell your doctor if you have liver
disease, heart disease, or a breathing disorder.
Cabergoline is usually taken twice each week for at least 6 months. Do
not take this medication every day unless your doctor tells you to.
Tell your doctor about all other medicines you use, especially blood
pressure medication.
You may have increased sexual urges, unusual urges to gamble, or other
intense urges while taking this medication. Talk with your doctor if
you believe you have any intense or unusual urges while taking
cabergoline.
To be sure this medication is helping your condition, your blood will
need to be tested on a regular basis to measure your prolactin levels.
Your doctor may want to continue checking your prolactin levels for
several months after you stop taking cabergoline. Visit your doctor
regularly.
Dostinex Patient Information including How Should I Take
RxList
Take the Kidney Disease Quiz
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What should I discuss with my health care provider before taking cabergoline
(Dostinex)?
You should not use this medication if you are allergic to cabergoline,
or if you have:
* uncontrolled high blood pressure (hypertension);
* hypertension caused by pregnancy, including eclampsia and
preeclampsia;
* a history of heart or breathing problems;
* if you have ever had a heart valve disorder; or
* if you are allergic to any type of ergot medicine such as
ergotamine (Ergomar, Cafergot, Migergot), dihydroergotamine (D.H.E.
45, Migranal), ergonovine (Ergotrate), or methylergonovine
(Methergine).
To make sure you can safely take cabergoline, tell your doctor if you
have any of these other conditions:
* liver disease;
* heart disease; or
* a breathing disorder.
FDA pregnancy category B. Cabergoline is not expected to harm an unborn
baby. Tell your doctor if you are pregnant or plan to become pregnant
during treatment.
It is not known whether cabergoline passes into breast milk or if it
could harm a nursing baby. You should not breast-feed while you are
using cabergoline.
How should I take cabergoline (Dostinex)?
Take exactly as prescribed by your doctor. Do not take in larger or
smaller amounts or for longer than recommended. Follow the directions
on your prescription label.
Your doctor will perform tests to make sure you do not have heart
conditions that would prevent you from safely using cabergoline. Your
heart function may also need to be checked using an electrocardiograph
or ECG (sometimes called an EKG). This machine measures electrical
activity of the heart.
Your doctor may occasionally change your dose to make sure you get the
best results.
Cabergoline is usually taken twice each week for at least 6 months. Do
not take this medication every day unless your doctor tells you to.
To be sure this medication is helping your condition, your blood will
need to be tested on a regular basis to measure your prolactin levels.
Your doctor may want to continue checking your prolactin levels for
several months after you stop taking cabergoline. Visit your doctor
regularly.
Store at room temperature away from moisture and heat.
Dostinex Patient Information including If I Miss a Dose
RxList
Take the Kidney Disease Quiz
Kidney Stones:Learn How to Prevent Them
Kidney Stone Slideshow Pictures
High Blood Pressure: Learn About Hypertension
High Blood Pressure Slideshow Pictures
What happens if I miss a dose (Dostinex)?
Take the missed dose as soon as you remember. Skip the missed dose if
it is almost time for your next scheduled dose. Do not take extra
medicine to make up the missed dose.
What happens if I overdose (Dostinex)?
Seek emergency medical attention or call the Poison Help line at
1-800-222-1222.
Overdose symptoms may include stuffy nose, hallucinations, or
fainting.
What should I avoid while taking cabergoline (Dostinex)?
Avoid getting up too fast from a sitting or lying position, or you may
feel dizzy. Get up slowly and steady yourself to prevent a fall.
What other drugs will affect cabergoline (Dostinex)?
Before using cabergoline, tell your doctor if you regularly use other
medicines that make you sleepy (such as cold or allergy medicine,
sedatives, narcotic pain medicine, sleeping pills, muscle relaxers,
and medicine for seizures, depression, or anxiety). They can add to
sleepiness caused by cabergoline.
Tell your doctor about all other medicines you use, especially:
* chlorpromazine (Thorazine);
* clarithromycin (Biaxin);
* droperidol (Inapsine);
* erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, and
others);
* fluphenazine (Permitil, Prolixin);
* haloperidol (Haldol);
* metoclopramide (Reglan);
* perphenazine (Trilafon);
* prochlorperazine (Compazine, Compro);
* promethazine (Pentazine, Phenergan, Anergan, Antinaus);
* thiothixene (Navane);
* thioridazine (Mellaril);
* trifluoperazine (Stelazine); or
* any type of blood pressure medication.
This list is not complete and other drugs may interact with
cabergoline. Tell your doctor about all medications you use. This
includes prescription, over-the-counter, vitamin, and herbal products.
Do not start a new medication without telling your doctor.
Where can I get more information (Dostinex)?
Your pharmacist can provide more information about cabergoline.
__________________________________________________________________
Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this
medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by
Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
but no guarantee is made to that effect. Drug information contained
herein may be time sensitive. Multum information has been compiled for
use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United
States are appropriate, unless specifically indicated otherwise.
Multum's drug information does not endorse drugs, diagnose patients or
recommend therapy. Multum's drug information is an informational
resource designed to assist licensed healthcare practitioners in caring
for their patients and/or to serve consumers viewing this service as a
supplement to, and not a substitute for, the expertise, skill,
knowledge and judgment of healthcare practitioners. The absence of a
warning for a given drug or drug combination in no way should be
construed to indicate that the drug or drug combination is safe,
effective or appropriate for any given patient. Multum does not assume
any responsibility for any aspect of healthcare administered with the
aid of information Multum provides. The information contained herein is
not intended to cover all possible uses, directions, precautions,
warnings, drug interactions, allergic reactions, or adverse effects. If
you have questions about the drugs you are taking, check with your
doctor, nurse or pharmacist.
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