* Generic Name: losartan potassium-hydrochlorothiazide
* Brand Name: Hyzaar
* What is hydrochlorothiazide and losartan (Hyzaar)?
* What are the possible side effects of hydrochlorothiazide and
losartan (Hyzaar)?
* What is the most important information I should know about
hydrochlorothiazide and losartan (Hyzaar)?
* What should I discuss with my healthcare provider before taking
hydrochlorothiazide and losartan (Hyzaar)?
* How should I take hydrochlorothiazide and losartan (Hyzaar)?
* What happens if I miss a dose (Hyzaar)?
* What happens if I overdose (Hyzaar)?
* What should I avoid while taking hydrochlorothiazide and
losartan (Hyzaar)?
* What other drugs will affect hydrochlorothiazide and losartan
(Hyzaar)?
* Where can I get more information (Hyzaar)?
What is hydrochlorothiazide and losartan (Hyzaar)?
Hydrochlorothiazide is a thiazide diuretic (water pill) that helps
prevent your body from absorbing too much salt, which can cause fluid
retention.
Losartan is an angiotensin II receptor antagonist. Losartan
keeps blood vessels from narrowing, which lowers blood pressure and
improves blood flow.
Hydrochlorothiazide and losartan is a combination medicine used to
treat high blood pressure (hypertension). It is also used to
lower the risk of stroke in certain people with heart disease.
Hydrochlorothiazide and losartan may also be used for purposes not
listed in this medication guide.
What are the possible side effects of hydrochlorothiazide and losartan
(Hyzaar)?
Get emergency medical help if you have signs of an allergic reaction:
hives; difficulty breathing; swelling of your face, lips, tongue, or
throat.
In rare cases, hydrochlorothiazide and losartan can cause a condition
that results in the breakdown of skeletal muscle tissue, leading to
kidney failure. Call your doctor right away if you have unexplained
muscle pain, tenderness, or weakness especially if you also
have fever, unusual tiredness, and dark colored urine.
Also call your doctor at once if you have:
* eye pain, vision problems;
* a light-headed feeling, like you might pass out;
* jaundice (yellowing of the skin or eyes);
* easy bruising, unusual bleeding;
* kidney problems--little or no urination, painful or difficult
urination, swelling in your feet or ankles, feeling tired or short
of breath;
* low levels of sodium in the body--headache, confusion, slurred
speech, severe weakness, vomiting, loss of coordination,
feeling unsteady;
* high potassium--nausea, slow or unusual heart rate, weakness, loss
of movement; or
* low potassium--leg cramps, constipation, irregular heartbeats,
fluttering in your chest, increased thirst or urination,
numbness or tingling, muscle weakness or limp feeling.
Common side effects may include:
* dizziness;
* cold symptoms such as stuffy nose, sneezing, sore
throat;
* cough; or
* back pain.
This is not a complete list of side effects and others may occur. Call
your doctor for medical advice about side effects. You may report side
effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about
hydrochlorothiazide and losartan (Hyzaar)?
Do not use if you are pregnant. If you become pregnant, stop taking
this medicine and tell your doctor right away.
You should not use this medicine if you are unable to urinate.
If you have diabetes, do not use hydrochlorothiazide and losartan
together with any medication that contains aliskiren (such as
Tekturna or Tekamlo).
Hyzaar Patient Information including How Should I Take
High Blood Pressure: Learn About Hypertension
High Blood Pressure Slideshow Pictures
RxList
Take the Salt Quiz!
Lowering Blood Pressure:Exercise Tips for Getting Started
Lowering Blood Pressure Exercise Tips Pictures
What should I discuss with my healthcare provider before taking
hydrochlorothiazide and losartan (Hyzaar)?
You should not use this medicine if you are allergic to
hydrochlorothiazide or losartan, if you are unable to urinate.
If you have diabetes, do not use hydrochlorothiazide and losartan
together with any medication that contains aliskiren (such as Tekturna
or Tekamlo).
You may also need to avoid taking hydrochlorothiazide and losartan with
aliskiren if you have kidney disease.
To make sure hydrochlorothiazide and losartan is safe for you, tell
your doctor if you have ever had:
* kidney disease;
* liver disease;
* congestive heart failure;
* glaucoma;
* low or high levels of potassium in your blood;
* asthma or allergies;
* high cholesterol or triglyceride levels;
* gout;
* lupus;
* diabetes; or
* an allergy to penicillin or sulfa drugs.
Do not use if you are pregnant. If you become pregnant, stop taking
this medicine and tell your doctor right away. Hydrochlorothiazide and
losartan can cause injury or death to the unborn baby if you take the
medicine during your second or third trimester.
Hydrochlorothiazide can pass into breast milk and may cause side
effects in the nursing baby. You should not breast-feed while using
this medicine.
How should I take hydrochlorothiazide and losartan (Hyzaar)?
Follow all directions on your prescription label. Your doctor may
occasionally change your dose. Do not take this medicine in larger or
smaller amounts or for longer than recommended.
Your blood pressure will need to be checked often.
Call your doctor if you have ongoing vomiting or diarrhea, or if you
are sweating more than usual. You can easily become dehydrated while
taking this medication, which can lead to severely low blood
pressure or a serious electrolyte imbalance.
If you need surgery or medical tests, tell the surgeon ahead of
time that you are using hydrochlorothiazide and losartan.
It may take up to 4 weeks for this medication to control your blood
pressure. Keep using this medicine as directed, even if you feel well.
High blood pressure often has no symptoms. You may need to use blood
pressure medication for the rest of your life.
Store at room temperature away from moisture, heat, and light.
Hyzaar Patient Information including If I Miss a Dose
High Blood Pressure: Learn About Hypertension
High Blood Pressure Slideshow Pictures
RxList
Take the Salt Quiz!
Lowering Blood Pressure:Exercise Tips for Getting Started
Lowering Blood Pressure Exercise Tips Pictures
What happens if I miss a dose (Hyzaar)?
Take the missed dose as soon as you remember. Skip the missed dose if
it is almost time for your next scheduled dose. Do not take extra
medicine to make up the missed dose.
What happens if I overdose (Hyzaar)?
Seek emergency medical attention or call the Poison Help line at
1-800-222-1222.
What should I avoid while taking hydrochlorothiazide and losartan (Hyzaar)?
If you also take cholestyramine or colestipol, avoid taking these
medications within 4 hours before or 4 hours after you take
hydrochlorothiazide and losartan.
Do not use potassium supplements or salt substitutes while you are
taking hydrochlorothiazide and losartan, unless your doctor has told
you to.
Drinking alcohol can further lower your blood pressure and may cause
side effects.
Avoid becoming overheated or dehydrated during exercise, in hot
weather, or by not drinking enough fluids.
What other drugs will affect hydrochlorothiazide and losartan (Hyzaar)?
Tell your doctor about all your current medicines and any you start or
stop using, especially:
* any other blood pressure medications;
* insulin or oral diabetes medicine;
* lithium; or
* NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen
(Advil, Motrin), naproxen (Aleve), celecoxib,
diclofenac, indomethacin, meloxicam, and others.
This list is not complete. Other drugs may interact with
hydrochlorothiazide and losartan, including prescription and
over-the-counter medicines, vitamins, and herbal products. Not all
possible interactions are listed in this medication guide.
Where can I get more information (Hyzaar)?
Your pharmacist can provide more information about hydrochlorothiazide
and losartan.
__________________________________________________________________
Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this
medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by
Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
but no guarantee is made to that effect. Drug information contained
herein may be time sensitive. Multum information has been compiled for
use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United
States are appropriate, unless specifically indicated otherwise.
Multum's drug information does not endorse drugs, diagnose patients or
recommend therapy. Multum's drug information is an informational
resource designed to assist licensed healthcare practitioners in caring
for their patients and/or to serve consumers viewing this service as a
supplement to, and not a substitute for, the expertise, skill,
knowledge and judgment of healthcare practitioners. The absence of a
warning for a given drug or drug combination in no way should be
construed to indicate that the drug or drug combination is safe,
effective or appropriate for any given patient. Multum does not assume
any responsibility for any aspect of healthcare administered with the
aid of information Multum provides. The information contained herein is
not intended to cover all possible uses, directions, precautions,
warnings, drug interactions, allergic reactions, or adverse effects. If
you have questions about the drugs you are taking, check with your
doctor, nurse or pharmacist.
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