* Generic Name: ketoconazole
* Brand Name: Nizoral
* What is ketoconazole (Nizoral)?
* What are the possible side effects of ketoconazole (Nizoral)?
* What is the most important information I should know about
ketoconazole (Nizoral)?
* What should I discuss with my healthcare provider before taking
ketoconazole (Nizoral)?
* How should I take ketoconazole (Nizoral)?
* What happens if I miss a dose (Nizoral)?
* What happens if I overdose (Nizoral)?
* What should I avoid while taking ketoconazole (Nizoral)?
* What other drugs will affect ketoconazole (Nizoral)?
* Where can I get more information (Nizoral)?
What is ketoconazole (Nizoral)?
Ketoconazole is an antifungal medication that fights infections
caused by fungus.
Ketoconazole is not for use in treating fungal infections of the
fingernails or toenails. This medicine is also not for use in treating
prostate cancer or Cushing syndrome.
This medicine should be used only when you cannot use other
antifungal medications. Ketoconazole can cause serious harm to your
liver that may result in liver transplant or cause death.
Ketoconazole may also be used for purposes not listed in this
medication guide.
What are the possible side effects of ketoconazole (Nizoral)?
Get emergency medical help if you have signs of an allergic reaction:
hives; fever; difficulty breathing, chest pain; swelling of your face,
lips, tongue, or throat.
Call your doctor at once if you have:
* headache with chest pain and severe dizziness, fainting, fast
or pounding heartbeats;
* unusual weakness or tired feeling, nausea and vomiting; or
* liver problems--upper stomach pain, itching, tired feeling,
loss of appetite, dark urine, clay-colored stools,
jaundice (yellowing of the skin or eyes);
Common side effects may include:
* mild nausea or stomach pain;
* diarrhea; or
* headache.
This is not a complete list of side effects and others may occur. Call
your doctor for medical advice about side effects. You may report side
effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about ketoconazole
(Nizoral)?
This medicine should be used only when you cannot use other antifungal
medications. Ketoconazole can cause serious harm to your liver that may
result in liver transplant or cause death.
Call your doctor at once if you have any signs of liver damage, such as
nausea, upper stomach pain, itching, tired feeling, loss of appetite,
dark urine, clay-colored stools, or jaundice (yellowing of the skin or
eyes).
Some medicines can interact with ketoconazole and should not be used at
the same time. Your doctor may need to change your treatment plan if
you use any of the following drugs: alprazolam, cisapride,
dihydroergotamine, disopyramide, dofetilide, dronedarone, eplerenone,
ergotamine, lovastatin, methadone, midazolam, nisoldipine,
pimozide, quinidine, ranolazine, simvastatin, or triazolam. Certain
drug interactions can cause life-threatening irregular heartbeats.
Call your doctor right away if you have a headache with chest pain and
severe dizziness, and fast or pounding heartbeats.
Nizoral Patient Information including How Should I Take
Fungal Infections: Fungus Among Us
Fungal Infections Slideshow: Fungus Among Us
RxList
Take the Tummy Trouble Quiz
Hepatitis C: Transmission, Symptoms and Treatment
Hepatitis C Slideshow Pictures
What should I discuss with my healthcare provider before taking ketoconazole
(Nizoral)?
You should not use ketoconazole if you are allergic to it, or if you
have liver disease.
Some medicines can interact with ketoconazole and should not be used at
the same time. Certain drug interactions can cause life-threatening
irregular heartbeats. Your doctor may need to change your treatment
plan if you use any of the following drugs:
* alprazolam, midazolam, or triazolam;
* cisapride or pimozide;
* dihydroergotamine or ergotamine;
* disopyramide, dofetilide, dronedarone, eplerenone, nisoldipine,
quinidine, or ranolazine;
* lovastatin or simvastatin; or
* methadone.
To make sure ketoconazole is safe for you, tell your doctor if you
have:
* any history of liver problems;
* problems with your adrenal gland;
* personal or family history of long QT syndrome; or
* if you also use certain antibiotics, heart rhythm medication,
migraine headache medicine, anti-malaria medication, or
medicine to treat depression or mental illness.
It is not known whether this medicine will harm an unborn baby. Tell
your doctor if you are pregnant.
Ketoconazole can pass into breast milk and may harm a nursing baby. You
should not breast-feed while using this medicine.
Do not give this medicine to a child without medical advice.
How should I take ketoconazole (Nizoral)?
Your doctor will perform blood tests to make sure you do not have
conditions that would prevent you from safely using ketoconazole.
Follow all directions on your prescription label. Do not take this
medicine in larger or smaller amounts or for longer than recommended.
Do not share this medicine with another person, even if they have the
same symptoms you have.
While using ketoconazole, you may need frequent blood tests to check
your liver function.
Use this medication for the full prescribed length of time. Your
symptoms may improve before the infection is completely cleared.
Skipping doses may also increase your risk of further infection that is
resistant to antifungal medicine. Ketoconazole will not treat a
viral infection such as the common cold or flu.
Store at room temperature away from moisture and heat.
Nizoral Patient Information including If I Miss a Dose
Fungal Infections: Fungus Among Us
Fungal Infections Slideshow: Fungus Among Us
RxList
Take the Tummy Trouble Quiz
Hepatitis C: Transmission, Symptoms and Treatment
Hepatitis C Slideshow Pictures
What happens if I miss a dose (Nizoral)?
Take the missed dose as soon as you remember. Skip the missed dose if
it is almost time for your next scheduled dose. Do not take extra
medicine to make up the missed dose.
What happens if I overdose (Nizoral)?
Seek emergency medical attention or call the Poison Help line at
1-800-222-1222.
What should I avoid while taking ketoconazole (Nizoral)?
Avoid taking antacids, stomach acid reducers, or medicines to treat
stomach ulcer or gastroesophageal reflux disease (Axid,
Nexium, Pepcid, Prevacid Prilosec, sucralfate,
Tagamet, Zantac, and others). These medications can make it
harder for your body to absorb ketoconazole.
Avoid drinking alcohol. It may increase your risk of liver damage while
you are taking ketoconazole.
What other drugs will affect ketoconazole (Nizoral)?
Many drugs can interact with ketoconazole. This includes prescription
and over-the-counter medicines, vitamins, and herbal products. Not all
possible interactions are listed here. Tell your doctor about all your
medications and any you start or stop using during treatment with
ketoconazole. Give a list of all your medicines to any healthcare
provider who treats you.
Where can I get more information (Nizoral)?
Your pharmacist can provide more information about ketoconazole.
__________________________________________________________________
Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this
medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by
Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
but no guarantee is made to that effect. Drug information contained
herein may be time sensitive. Multum information has been compiled for
use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United
States are appropriate, unless specifically indicated otherwise.
Multum's drug information does not endorse drugs, diagnose patients or
recommend therapy. Multum's drug information is an informational
resource designed to assist licensed healthcare practitioners in caring
for their patients and/or to serve consumers viewing this service as a
supplement to, and not a substitute for, the expertise, skill,
knowledge and judgment of healthcare practitioners. The absence of a
warning for a given drug or drug combination in no way should be
construed to indicate that the drug or drug combination is safe,
effective or appropriate for any given patient. Multum does not assume
any responsibility for any aspect of healthcare administered with the
aid of information Multum provides. The information contained herein is
not intended to cover all possible uses, directions, precautions,
warnings, drug interactions, allergic reactions, or adverse effects. If
you have questions about the drugs you are taking, check with your
doctor, nurse or pharmacist.
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