* Generic Name: repaglinide
* Brand Name: Prandin
* What is repaglinide (Prandin)?
* What are the possible side effects of repaglinide (Prandin)?
* What is the most important information I should know about
repaglinide (Prandin)?
* What should I discuss with my healthcare provider before taking
repaglinide (Prandin)?
* How should I take repaglinide (Prandin)?
* What happens if I miss a dose (Prandin)?
* What happens if I overdose (Prandin)?
* What should I avoid while taking repaglinide (Prandin)?
* What other drugs will affect repaglinide (Prandin)?
* Where can I get more information (Prandin)?
What is repaglinide (Prandin)?
Repaglinide is an oral diabetes medicine that helps control blood
sugar levels by causing the pancreas to produce insulin.
Repaglinide is used together with diet and exercise to improve
blood sugar control in adults with type 2 diabetes mellitus. This
medicine is not for treating type 1 diabetes.
Repaglinide may also be used for purposes not listed in this medication
guide.
What are the possible side effects of repaglinide (Prandin)?
Get emergency medical help if you have signs of an allergic reaction:
hives; difficulty breathing; swelling of your face, lips, tongue, or
throat.
Call your doctor at once if you have:
* severe pain in your upper stomach spreading to your back,
nausea and vomiting, fast heart rate;
* pale or yellowed skin, dark colored urine, fever, confusion or
weakness; or
* severe skin reaction--fever, sore throat, swelling in your face
or tongue, burning in your eyes, skin pain, followed by a red or
purple skin rash that spreads (especially in the face or upper
body) and causes blistering and peeling.
Common side effects may include:
* low blood sugar;
* nausea, diarrhea;
* headache, back pain;
* joint pain; or
* cold symptoms such as stuffy nose, sneezing, sore
throat.
This is not a complete list of side effects and others may occur. Call
your doctor for medical advice about side effects. You may report side
effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about repaglinide
(Prandin)?
You should not use repaglinide if you have type 1 diabetes, severe
liver disease, or diabetic ketoacidosis.
You should not use repaglinide together with gemfibrozil
(Lopid) or NPH insulin (such as isophane insulin).
Prandin Patient Information including How Should I Take
Type 2 Diabetes Diagnosis, Treatment, Medication
Type 2 Diabetes: Learn the Warning Signs
Diabetes: Best and Worst Meals for Diabetes-Savvy Dining
Diabetes Friendly Dining
RxList
Type 2 Diabetes Quiz
What should I discuss with my healthcare provider before taking repaglinide
(Prandin)?
You should not use repaglinide if you are allergic to it, or if you
have:
* severe liver disease;
* diabetic ketoacidosis (call your doctor for treatment with
insulin); or
* if you also take gemfibrozil.
To make sure repaglinide is safe for you, tell your doctor if you have:
* liver disease; or
* if you also take metformin or other diabetes medicines.
Follow your doctor's instructions about using this medicine if you are
pregnant. Blood sugar control is very important during pregnancy, and
your dose needs may be different during each trimester.
It is not known whether repaglinide passes into breast milk or if it
could harm a nursing baby. You should not breast-feed while using this
medicine.
Repaglinide is not approved for use by anyone younger than 18 years
old.
How should I take repaglinide (Prandin)?
Follow all directions on your prescription label. Your doctor may
occasionally change your dose. Do not take this medicine in larger or
smaller amounts or for longer than recommended.
Repaglinide is usually taken 2 to 4 times daily, within 30 minutes
before eating a meal. Follow your doctor's instructions. If you skip a
meal, do not take your dose of repaglinide. Wait until your next meal.
Your blood sugar will need to be checked often, and you may need other
blood tests at your doctor's office.
Low blood sugar (hypoglycemia) can happen to everyone who has diabetes.
Symptoms include headache, hunger, sweating, irritability, dizziness,
nausea, fast heart rate, and feeling anxious or shaky. To quickly treat
low blood sugar, always keep a fast-acting source of sugar with you
such as fruit juice, hard candy, crackers, raisins, or non-diet soda.
Your doctor can prescribe a glucagon emergency injection kit to use
in case you have severe hypoglycemia and cannot eat or drink. Be
sure your family and close friends know how to give you this injection
in an emergency.
Blood sugar levels can be affected by stress, illness, surgery,
exercise, alcohol use, or skipping meals. Ask your doctor before
changing your dose or medication schedule.
Repaglinide is only part of a treatment program that may also include
diet, exercise, weight control, blood sugar testing, and special
medical care. Follow your doctor's instructions very closely.
Store repaglinide at room temperature away from moisture and heat.
Prandin Patient Information including If I Miss a Dose
Type 2 Diabetes Diagnosis, Treatment, Medication
Type 2 Diabetes: Learn the Warning Signs
Diabetes: Best and Worst Meals for Diabetes-Savvy Dining
Diabetes Friendly Dining
RxList
Type 2 Diabetes Quiz
What happens if I miss a dose (Prandin)?
Take the missed dose as soon as you remember, but only if you are
getting ready to eat a meal. Skip the missed dose if it is almost time
for your next scheduled dose. Do not take extra medicine to make up the
missed dose.
What happens if I overdose (Prandin)?
Seek emergency medical attention or call the Poison Help line at
1-800-222-1222. A repaglinide overdose can cause life-threatening
hypoglycemia.
Symptoms of severe hypoglycemia include extreme weakness, blurred
vision, sweating, trouble speaking, tremors, stomach pain,
confusion, and seizure (convulsions).
What should I avoid while taking repaglinide (Prandin)?
Avoid drinking alcohol. It lowers blood sugar and may interfere with
your diabetes treatment.
What other drugs will affect repaglinide (Prandin)?
Many other medicines that can increase or decrease the effects of
repaglinide on lowering your blood sugar. This includes prescription
and over-the-counter medicines, vitamins, and herbal products. Tell
each of your health care providers about all medicines you use now and
any medicine you start or stop using.
Where can I get more information (Prandin)?
Your pharmacist can provide more information about repaglinide.
__________________________________________________________________
Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this
medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by
Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
but no guarantee is made to that effect. Drug information contained
herein may be time sensitive. Multum information has been compiled for
use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United
States are appropriate, unless specifically indicated otherwise.
Multum's drug information does not endorse drugs, diagnose patients or
recommend therapy. Multum's drug information is an informational
resource designed to assist licensed healthcare practitioners in caring
for their patients and/or to serve consumers viewing this service as a
supplement to, and not a substitute for, the expertise, skill,
knowledge and judgment of healthcare practitioners. The absence of a
warning for a given drug or drug combination in no way should be
construed to indicate that the drug or drug combination is safe,
effective or appropriate for any given patient. Multum does not assume
any responsibility for any aspect of healthcare administered with the
aid of information Multum provides. The information contained herein is
not intended to cover all possible uses, directions, precautions,
warnings, drug interactions, allergic reactions, or adverse effects. If
you have questions about the drugs you are taking, check with your
doctor, nurse or pharmacist.
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